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Peer-reviewed veterinary case report

Irish setter with eye inflammation caused by epitheliotropic lymphoma

By Donaldson, D & Day, M J·Published in The Journal of small animal practice·2000·Department of Pathology and Microbiology, United Kingdom·View original on PubMed

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Original publication title: Epitheliotropic lymphoma (mycosis fungoides) presenting as blepharoconjunctivitis in an Irish setter.

Plain-English summary

An 11-year-old neutered female Irish setter was brought in with a six-week history of eye problems, specifically swelling and irritation in her right eye. After taking a small sample from the eye's surface for testing, the vet found that the dog had a type of cancer called epitheliotropic lymphoma (mycosis fungoides), which affects the skin and eyes. To treat her condition, the veterinarian used a synthetic retinoid and topical prednisolone, a type of steroid. The outcome of the treatment is not specified, but these medications are commonly used to manage similar cases.

People also search for: Irish setter eye problems · dog blepharoconjunctivitis treatment · mycosis fungoides in dogs

Abstract

An 11-year-old neutered female Irish setter was presented with a six-week history of blepharoconjunctivitis affecting the right eye. A conjunctival biopsy was taken and histopathological examination revealed a heavy cellular infiltrate involving the epithelial and subepithelial tissues. Immunohistochemical staining showed the intraepithelial cell population to uniformly have the phenotype CD3 (T-cell specific marker). A diagnosis of epitheliotropic lymphoma (mycosis fungoides) was made. The use of a synthetic retinoid and topical prednisolone in the management of the case is discussed.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10976628/