Peer-reviewed veterinary case report
Equine papillary ependymoma.
- Journal:
- Veterinary pathology
- Year:
- 1996
- Authors:
- Carrigan, M J et al.
- Species:
- horse
Plain-English summary
A 17-year-old Arabian gelding was showing signs of worsening neurological problems, and a reddish, velvety tumor was found in his brain, located near the optic nerves. The tumor was identified as a papillary ependymoma, which is a type of brain tumor. The cells in the tumor had specific features that helped veterinarians confirm the diagnosis. Unfortunately, the abstract does not provide information on treatment or the outcome for this horse.
Abstract
A 17-year-old Arabian gelding with progressive neurologic signs had a velvety, reddish brain tumor protruding from the ventral midline caudal to the optic chiasma. Histologically, the tumor had a papillary formation with a single layer of elongate cells radially oriented around a central fibrovascular core. Intracytoplasmic globular inclusions were positive for glial fibrillary acidic protein and weakly positive for vimentin. Ultrastructurally, these inclusions were comprised of whorling intermediate filaments. Neoplastic cells also had cytoplasmic interdigitations and numerous zona adherens and often rested on a basal lamina. The tumor was diagnosed as a papillary ependymoma.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/8826009/