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Peer-reviewed veterinary case report

Sudden skin plaques on horses - what is erythema multiforme?

By Marshall, C·Published in Journal of the South African Veterinary Association·1991·Department of Companion Animal Medicine and Surgery·View original on PubMed

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Original publication title: Erythema multiforme in two horses.

Species:
horse

Plain-English summary

Erythema multiforme, a skin condition, was seen for the first time in two horses from South Africa. Both horses suddenly developed raised, red patches on their necks and bodies that were not itchy and did not cause hair loss. The patches appeared in a symmetrical pattern on both sides of their bodies. Although the exact cause of this condition was not found, both horses improved on their own over a period of three months.

Abstract

Erythema multiforme is reported for the first time in 2 South African horses. Both horses displayed a sudden, fulminant outbreak of raised, non-alopecic and non-pruritic plaques over the dorsolateral aspects of the neck and trunk. In both cases the distribution of the lesions was bilaterally symmetrical. Histopathological findings included hydropic degeneration of basal epidermal cells, eosinophilic necrosis of individual or groups of keratinocytes, intra-epidermal and sub-epidermal cleft formation and mixed, dermal, perivascular infiltrates. An initiating cause could not be identified in either case. Both horses underwent gradual spontaneous remission within 3 months.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/1770484/