Peer-reviewed veterinary case report
Spongiotic vesicular dermatitis as a cutaneous reaction pattern in seven horses.
- Journal:
- Veterinary dermatology
- Year:
- 2001
- Authors:
- Hargis, A M et al.
- Affiliation:
- Dermato Diagnostics · United States
- Species:
- horse
Plain-English summary
Over a six-year study, seven adult horses of various breeds and genders developed skin issues that caused areas of oozing and inflammation. Some of these horses experienced intense itching, but there were no signs of a broader illness affecting their overall health. A couple of the horses had a history of hives, and one had skin bumps that turned into the oozing lesions. Tests showed changes in their skin that suggested fluid buildup rather than a specific immune response. The treatment for these skin issues was not detailed, but the study indicates that the lesions were linked to a specific type of skin reaction rather than a systemic disease.
Abstract
Over a 6-year period seven adult horses of different breeds and genders developed multifocal, exudative, oozing dermatitis characterized histologically by epidermal spongiotic vesicles and perivascular eosinophilic, neutrophilic and mixed mononuclear inflammation. Three horses were pruritic. Systemic disease was not noted. Two horses had a history of recurrent urticaria (hives) and one horse had nodules or welt-type lesions that progressed to exudative, oozing lesions. Interepithelial immunoglobulin (Ig)G was detected by avidin-biotin complex-peroxidase staining, but the pattern of staining was more consistent with epithelial oedema than specific IgG deposition associated with pemphigus. The exudative oozing lesions developed under circumstances suggesting that dermal oedema progressed to intracellular and intercellular epidermal oedema, which in turn progressed to the spongiotic vesicular epidermal lesions.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/11906655/