Peer-reviewed veterinary case report
E coli granulomatous diseases affecting organs in three cats
By Paz, Milena C et al.·Published in Journal of comparative pathology·2025·Setor de Patologia Veteriná, Brazil·View original on PubMed →
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Original publication title: Escherichia coli-associated granulomatous diseases in three cats.
- Species:
- cat
Plain-English summary
Three cats were diagnosed with unusual infections caused by E. coli, leading to serious health issues. One cat had a problem in its urinary bladder called malakoplakia, while the other two suffered from granulomatous enteritis, which affected their intestines and lymph nodes. These conditions are rare in cats and can cause symptoms like vomiting or diarrhea. Treatment details weren't specified, but early diagnosis and appropriate care are crucial for recovery.
People also search for: cat vomiting E. coli infection · cat diarrhea treatment · malakoplakia in cats
Abstract
Granulomatous diseases associated with Escherichia coli infection are uncommon in domestic animals. In cats, malakoplakia and granulomatous ulcerative colitis are the only described forms. We investigated the clinical and pathological findings of E. coli-associated granulomatous diseases in three cats. In all cases the affected organs were infiltrated by many macrophages containing periodic acid-Schiff-positive intracytoplasmic granules. The macrophages immunolabelled for ionized calcium-binding adapter molecule 1 and E. coli. The first case involved the urinary bladder and was diagnosed as malakoplakia. The second case had small intestinal granulomatous enteritis and lymphadenitis of the mesenteric, celiac, colonic, mandibular and mediastinal lymph nodes. The third case had granulomatous enteritis, splenitis and lymphadenitis of the mesenteric, iliac, aortic, renal, hypogastric and sacral lymph nodes. Peyer's patches were predominantly affected in the small intestines of both the second and third cases. Although malakoplakia has been documented previously, the findings in the second and third cases suggest novel forms of granulomatous disease associated with E. coli in cats, with notable primary involvement of lymphoid tissue.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39970836/