Peer-reviewed veterinary case report
Dog with essential thrombocythemia treated successfully with chemo
By Mizukoshi, Takeshi et al.·Published in The Journal of veterinary medical science·2006·Sanyo Animal Medical Center, Japan·View original on PubMed →
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Original publication title: Essential thrombocythemia in a dog.
- Species:
- dog
Plain-English summary
A 2-year-old male Welsh Corgi was brought to the vet for ongoing high platelet counts and occasional seizures. Blood tests showed not only high platelets but also other abnormalities like low red blood cells. A bone marrow test confirmed a rare condition called essential thrombocythemia, which affects blood cell production. The dog was treated with a combination of chemotherapy and medications, and after 100 days, he was in complete remission and has been healthy without further treatment since then.
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Abstract
A two-year old male Welsh Corgi was referred for persistent thrombocytosis and occasional seizure. Hematological findings indicated marked thrombocytosis, eosinophilia, basophilia and moderate anemia. Bone marrow examination revealed marked megakaryocytic hyperplasia with morphologic abnormality. A diagnosis of essential thrombocythemia was made and the treatment was initiated with combination chemotherapy and maintained by prednisolone and busulfan. The dog successfully achieved complete remission on 100 days after initial presentation and has been good in health without chemotherapy since then.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17146180/