Peer-reviewed veterinary case report
Normal urine albumin-to-creatinine ratio range in healthy dogs
By Falus, Fruzsina Anna et al.·Published in Veterinary clinical pathology·2022·Department of Internal Medicine·View original on PubMed →
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Original publication title: Establishment of a reference interval for urinary albumin-to-creatinine ratio in dogs.
- Species:
- dog
Plain-English summary
A study looked at the levels of a protein called albumin in the urine of healthy dogs to help identify early signs of kidney disease. Researchers found that the normal range for the urinary albumin-to-creatinine (UAC) ratio in dogs is between 0 and 19 mg/g. This information can help veterinarians assess kidney health and detect issues before they become serious. The findings suggest that monitoring albumin levels in urine could be a useful tool in diagnosing kidney problems in dogs.
People also search for: dog kidney disease symptoms · urinary albumin test for dogs · how to check dog kidney health
Abstract
BACKGROUND: Albuminuria is an important marker of renal damage and can precede proteinuria; thus, it can be a useful analyte in the early diagnosis of kidney diseases. Albuminuria has also been found in dogs with hypertension, inflammatory, infectious, and neoplastic diseases. OBJECTIVES: The aim of this study was to establish a reference interval (RI) for albuminuria in dogs. METHODS: One hundred sixty-four clinically healthy dogs were enrolled in the study. Urinary albumin was determined by the immunoturbidimetric method, and albumin excretion was expressed as the urinary albumin-to-creatinine (UAC) ratio. The RI for UAC was established. RESULTS: After exclusions, 124 dogs from 32 breeds remained. The median UAC of the study population was 3.0 mg/g (range: 0-48). The RI was defined as 0-19 mg/g (with a 90% CI for the upper limit of 13-28 mg/g). No significant difference was found between male and female dogs or between different age and body weight groups. The results of Sighthounds (n = 30) and Beagle dogs (n = 23) did not differ from the other breeds. CONCLUSION: The canine RI of UAC is similar but somewhat narrower than the human RI.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35791959/