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Peer-reviewed veterinary case report

Dog with chest fungal tumor from Cladophialophora bantiana

By Guillot, J et al.·Published in Journal of clinical microbiology·2004·Service de Parasitologie-Mycologie, France·View original on PubMed

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Original publication title: Eumycetoma caused by Cladophialophora bantiana in a dog.

Species:
dog

Plain-English summary

A 3-year-old male Siberian Husky in France had a noticeable swelling on his chest and some rib deformities. After surgery to remove the affected ribs, the vet found black granules that turned out to be caused by a fungus called Cladophialophora bantiana. The dog was treated with antifungal medications, including itraconazole and flucytosine, and after 10 months, he appeared to be fully cured. The vet also considered that exposure to certain caterpillars and steroid treatments might have made the dog more susceptible to this infection.

People also search for: dog chest swelling · Siberian Husky fungal infection · eumycetoma treatment in dogs

Abstract

We report a case of eumycetoma due to Cladophialophora bantiana in a 3-year-old male Siberian Husky living in France. The dog presented a tumefaction on the thorax and deformity of the second and third subjacent ribs, which were surgically removed. Macroscopic black granules were visible on the ribs, and direct microscopic examination revealed their fungal origin. Cultures yielded pure colonies of C. bantiana. The identification of the causative agent was confirmed after amplification and sequence analysis of fungal internal transcribed spacers 1 and 2 and 5.8S ribosomal DNA regions. Surgery and antifungal treatment with oral itraconazole associated with flucytosine allowed apparent cure after a 10-month follow-up. Envenomation with pine processionary caterpillars (Thaumetopoea pityocampa) and subsequently intensive corticotherapy were considered as possible predisposing factors. This is, to the best of our knowledge, the first case in which C. bantiana is identified as the causative agent of eumycetoma.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15472377/