Peer-reviewed veterinary case report
Rapid ELISA test accurately detects Leishmania infection in dogs
By Ferroglio, E et al.·Published in Veterinary parasitology·2007·Dipartimento di Produzioni Animali, Italy·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Evaluation of an ELISA rapid device for the serological diagnosis of Leishmania infantum infection in dog as compared with immunofluorescence assay and Western blot.
- Species:
- dog
Plain-English summary
A study tested a new rapid blood test for Leishmania infection in dogs, which can cause serious health issues. The test, called Snap CLATK, was compared to two other methods and showed high accuracy, detecting 91% of positive cases and 99% of negative cases. It was also effective when using whole blood samples. This means that if your dog is at risk for Leishmania, the Snap CLATK test could provide a quick and reliable way to check for the infection, helping your vet decide on the best treatment options.
People also search for: dog Leishmania test · symptoms of Leishmania in dogs · Leishmania treatment for dogs
Abstract
In this study we compared a commercial enzyme linked immunosorbent assay (ELISA) rapid test (Snap CLATK Canine Leishmania Antibody Test Kit, IDEXX-Snap) with indirect immunofluorescence assay (IFA) and Western blot (WB) for the detection of Leishmania infantum antibodies in dogs. In total sera from 234 dogs were collected: 59 positives and 51 doubtful sera (IFA 1:40-1:80) from an L. infantum endemic area and 124 negative sera from a non-endemic area were tested. To evaluate the Snap CLATK's performances on whole blood, blood in EDTA and sera from 37 dogs were tested in parallel with Snap CLATK. Snap CLATK sensitivity and specificity compared to IFA were 91.1% and 99.2%, while compared to WB were 93.4% and 98.3%, respectively. When IFA doubtful sera (titers of 1:40 or 1:80) were tested Snap CLATK, using WB as reference, sensitivity and specificity were 90.9% and 100%, respectively. Moreover, a complete concordance was observed when Snap CLATK rapid assay was carried out on whole blood or sera from 37 dogs. The Snap CLATK has demonstrated simplicity and performance and can be considered a quick and reliable alternative for the diagnosis of L. infantum infection in dogs.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17046162/