Peer-reviewed veterinary case report
Blood oxidant and antioxidant levels in dogs with sarcoptic mange
By Camkerten, Ilker et al.·Published in Veterinary parasitology·2009·Department of Internal Medicine·View original on PubMed →
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Original publication title: Evaluation of blood oxidant/antioxidant balance in dogs with sarcoptic mange.
- Species:
- dog
Plain-English summary
A group of 15 male cross-breed dogs with sarcoptic mange (a skin condition caused by mites) showed signs of oxidative stress, which means their bodies had an imbalance between harmful substances and protective antioxidants. Blood tests revealed higher levels of oxidants and lower levels of protective compounds in these dogs compared to 15 healthy dogs. While the overall antioxidant capacity didn't differ significantly, the findings suggest that the skin condition may be linked to this imbalance. Treatment for sarcoptic mange typically includes medicated baths and topical treatments, which can help alleviate symptoms and improve skin health.
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Abstract
The aim of this study was to investigate of oxidant/antioxidant balance in dogs with sarcoptic mange. The study materials consisted of totally 30 cross-breed male dogs; 15 with sarcoptic mange (study group) and 15 healthy as control. Blood samples for analyses were taken from control and study group. In study group, microscopic examination of dermal scrapings of 15 dogs revealed S. scabies. Lipid hydroperoxide level, total oxidant status and oxidative stress index in dogs with sarcoptic mange were higher (P<0.01, P<0.01 and P<0.05, respectively) than the control. Otherwise; sulphydril levels in dogs with sarcoptic mange were lower (P<0.05) than that of control. No significant differences were observed in total antioxidant capacity between groups. Our results suggest a possible relationship between oxidant/antioxidant imbalance and sarcoptic mange infestation in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19211189/