Peer-reviewed veterinary case report
Bone marrow tests from one site usually enough to stage lymphoma
By Aubry, O A et al.·Published in Veterinary and comparative oncology·2014·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Evaluation of bone marrow aspirates from multiple sites for staging of canine lymphoma and mast cell tumours.
- Species:
- dog
Plain-English summary
A group of dogs with lymphoma and mast cell tumors underwent tests to see if taking bone marrow samples from multiple locations was necessary for accurate staging. Out of 33 dogs, 19 had lymphoma, and about one-third showed cancer cells in their bone marrow. For the dogs with mast cell tumors, about one in five had cancer cells in their bone marrow. The findings suggest that testing from multiple sites may not be needed for lymphoma, but further research is needed for mast cell tumors.
People also search for: dog lymphoma bone marrow test · mast cell tumor treatment in dogs · dog cancer staging methods
Abstract
This prospective study evaluated the utility of bone marrow aspirates (BMAs) obtained from multiple sites for staging of canine lymphoma (LSA) and mast cell tumours (MCTs). Forty dogs (LSA, n = 24; MCTs, n = 16) were enrolled, but only 33 (82.5%) had diagnostic bone marrow (BM) aspirates obtained from two sites for inclusion in the study. Nineteen dogs with LSA were included, and 6 (31.6%) had BM involvement. Neoplastic lymphocytes were present in BM from both sites in all of these dogs. Fourteen dogs with MCTs were included, and 3 (21.4%) had BM involvement. Neoplastic mast cells were present at both sites in two dogs and at only one site in the third. These results indicate that BMAs from multiple sites may not be needed for accurate staging of canine LSA patients, but more studies evaluating the pattern of BM infiltration in dogs with high-grade MCTs are warranted.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22577893/