Peer-reviewed veterinary case report
Inflammation markers in domestic cats infected with Cystoisospora
By Attia, Marwa M et al.·Published in BMC veterinary research·2024·Department of Parasitology·View original on PubMed →
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Original publication title: Evaluation of different inflammatory markers during the infection of domestic cats (Felis catus) by Cystoisospora felis (Coccidia: Apicomplexa).
- Species:
- cat
Plain-English summary
A group of 370 domestic cats in Cairo and Giza were tested for diarrhea caused by a parasite called Cystoisospora felis (a type of coccidia). Out of these cats, 27 were found to be infected, with higher infection rates in older female cats. The study measured stress markers in the infected cats, indicating that the parasite increases oxidative stress in their bodies. The researchers suggest that these cats may need a new treatment plan that uses safe and effective medications to help them recover without causing resistance.
People also search for: cat diarrhea treatment · Cystoisospora felis symptoms · cat stress treatment · how to treat coccidia in cats · cat infection treatment options
Abstract
BACKGROUND: Cystoisospora felis or Isospora felis is a ubiquitous apicomplexan protozoon parasite infecting domestic cats worldwide. OBJECTIVES OF THE STUDY: this study aims to identify the causative agent of diarrhea in cats by determining several elevating stressors caused by these coccidian protozoans with molecular characterization. So, from January 2023 to April 2023, a total of 370 domestic cats were hospitalized at various clinics in the Cairo and Giza Governorates. Fecal samples were taken from these animals and examined by concentration floatation techniques using a saturated salt solution. The positive samples were sporulated to identify the collected oocyst. Venous blood was taken from the infected cats to evaluate the associated oxidative stress marker (lipid peroxidation products (MDA). RESULTS: Out of 370 examined domestic cats, 27(7.29%) were positive for C. felis. The MDA levels increased with age, and females were higher than males. DNA was extracted from fecal samples for amplification of the ITS1 gene, followed by sequencing. The ITS1 gene was amplified and showed bands at 224 bp. The partial nucleotide sequence of the ITS1 gene was aligned with the reference sequences. IN A CONCLUSION: C. felis increases the free radicals, which in turn means the animals have stress and need a schedule to treat these animals with new, safe protocol drugs that give no resistance and are highly efficient.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39548486/