Peer-reviewed veterinary case report
What affects survival time in dogs with lymphoma
By Jeong, Soo-Yeon·Published in Open veterinary journal·2023·Department of Companion Animal Health Care, South Korea·View original on PubMed →
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Original publication title: Evaluation of factors influencing survival time in 77 dogs with lymphoma.
- Species:
- dog
Plain-English summary
A group of 77 dogs diagnosed with lymphoma (a type of cancer) was studied to find out what factors might affect how long they live after treatment. Researchers found that certain blood abnormalities, like low white blood cells and platelets, were linked to shorter survival times. On the other hand, dogs that had less gastrointestinal side effects and improvements in their blood counts during chemotherapy tended to live longer. Sticking closely to treatment plans and using multiple medications when needed also helped extend their lives.
People also search for: dog lymphoma survival rate · chemotherapy side effects in dogs · factors affecting dog cancer treatment outcomes
Abstract
BACKGROUND: Canine lymphoma is one of the most commonly reported hematopoietic tumors. AIM: A few retrospective studies have involved complex evaluations including diagnostic features and treatment protocols, but these studies infrequently demonstrate variable factors that affect survival time, and comparisons among chemotherapeutic protocols are limited. This study aimed to identify prognostic factors that can be simply detected in dogs with lymphoma, such as abnormalities in physical and hematologic findings, and treatment protocols. METHODS: Clinical records of 77 dogs diagnosed with lymphoma were retrospectively reviewed. RESULTS: The author newly identified leukocyte and platelet abnormalities as negative prognostic factors. Furthermore, this study suggests that decreased gastrointestinal toxicity and improvements of hematologic abnormalities, such as anemia, thrombocytopenia, and lymphocytosis or lymphoblasts, in peripheral blood during chemotherapy act as positive prognostic factors. Finally, strict adherence to therapeutic protocol and selecting multiple agents as rescue protocol are important to prolong survival time. CONCLUSION: This study identified indicators to be used as prognostic factors through survival analysis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37842100/