Peer-reviewed veterinary case report
Microwave treatment for bone cancer in dogs' front legs
By Salyer, Sarah A et al.·Published in Veterinary surgery : VS·2020·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: Evaluation of microwave ablation for local treatment of dogs with distal radial osteosarcoma: A pilot study.
- Species:
- dog
Plain-English summary
A group of six dogs with osteosarcoma (a type of bone cancer) in the lower leg underwent a new treatment called microwave ablation to help reduce the tumor before amputation. The procedure was done safely under anesthesia, and the dogs showed varying degrees of tumor shrinkage, with some experiencing up to 90% necrosis (death of cancer cells). Importantly, there were no complications during or after the treatment. This pilot study suggests that microwave ablation could be a promising option for treating bone tumors in dogs, but more research is needed to confirm its effectiveness.
People also search for: dog osteosarcoma treatment · microwave ablation for dogs · dog bone cancer symptoms
Abstract
OBJECTIVE: To evaluate the feasibility and safety of microwave ablation (MWA) as a modality to induce tumor necrosis within distal radial osteosarcoma (OSA). STUDY DESIGN: Pilot study. ANIMALS: Six client-owned dogs with distal radius OSA confirmed by cytological examination. METHODS: Dogs underwent computed tomography for surgical planning before general anesthesia for fluoroscopy-guided ablation. Computed tomography was repeated 48 hours after MWA, before amputation. The ablated tumor was evaluated with histopathology. RESULTS: Six dogs underwent MWA of distal radius OSA. A lower power setting (30 W) was selected for the first two dogs to avoid collateral soft tissue damage. The power was increased to 75 W for the last four dogs. The temperature was maintained between 45°C and 55°C (113 °F-131 °F) at the bone/soft tissue interface. Tumor necrosis varied between 30% and 90% (median, 55%) according to histopathology. No intraoperative or periprocedural complications were observed. CONCLUSION: Microwave ablation induced variable tumor necrosis and did not induce immediate postablation complications in these six dogs with distal radius OSA. CLINICAL SIGNIFICANCE: These results justify further evaluation of MWA as a potential modality to treat primary bone lesions in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32697356/