Peer-reviewed veterinary case report
Microwave treatment for lung tumors in two dogs with bone cancer
By Dornbusch, Josephine A et al.·Published in Veterinary surgery : VS·2020·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: Percutaneous microwave ablation of solitary presumptive pulmonary metastases in two dogs with appendicular osteosarcoma.
- Species:
- dog
Plain-English summary
Two large-breed dogs with lung nodules after treatment for bone cancer (appendicular osteosarcoma) underwent a procedure called microwave ablation to target these growths. This minimally invasive treatment was guided by imaging techniques and was performed successfully, with only one dog experiencing a minor complication (a small lung collapse). After the procedure, both dogs seemed to be doing well at home for a while, but unfortunately, one dog passed away and the other was euthanized a few months later due to the progression of their disease. This approach shows promise as a treatment option for lung metastases from osteosarcoma, but more research is needed to understand its long-term benefits.
People also search for: dog lung cancer treatment · microwave ablation for dogs · osteosarcoma in dogs prognosis
Abstract
OBJECTIVE: To describe percutaneous microwave ablation (MWA) of presumptive pulmonary metastases and the outcome of two dogs. ANIMALS: Two dogs with pulmonary lesions after treatment of spontaneously occurring appendicular osteosarcoma. STUDY DESIGN: Preliminary prospective clinical study. METHODS: Two large-breed dogs were referred from tertiary veterinary hospitals 146 and 217 days after limb amputation to pursue MWA as an alternative therapy to metastasectomy. Both dogs had been receiving chemotherapy protocols at their respective referral centers. RESULTS: A novel percutaneous approach for MWA with ultrasonographic or computed tomographic (CT) guidance was successfully performed. The only complications consisted of pneumothoraxes, requiring treatment in one dog. In the weeks after their procedures, both dogs were reported to do well at home. Dog 1 died and dog 2 was euthanized 82 and 19 days, respectively, after their MWA of confirmed (dog 1) or presumed (dog 2) metastatic disease. CONCLUSION: Percutaneous MWA of pulmonary nodules was technically feasible in two dogs without major complications. CLINICAL SIGNIFICANCE: Percutaneous MWA may provide a minimally invasive option for treatment of osteosarcoma pulmonary metastases. Additional studies are required to evaluate the benefits of MWA on survival and confirm histologic cell death within pulmonary neoplastic lesions.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32521058/