Peer-reviewed veterinary case report
Factors affecting survival in dogs with lymphoma
By Keller, Evan T. et al.·Published in Journal of Veterinary Internal Medicine·1993·School of Veterinary Medicine, University of Wisconsin Department of Medical Sciences, , Madison, WI·View original on Crossref →
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Original publication title: Evaluation of Prognostic Factors and Sequential Combination Chemotherapy With Doxorubicin for Canine Lymphoma
- Species:
- dog
Plain-English summary
Fifty-five dogs with lymphoma were treated with a chemotherapy drug called doxorubicin. Most dogs (46) showed a complete response to the treatment, while a few had partial or no response. On average, dogs remained in remission for about 36 weeks and lived for about 51 weeks after starting treatment. Factors like the dog's sex and health status were found to influence how long they stayed in remission and their overall survival. The study suggests that dogs in better health at the start of treatment tend to do better.
People also search for: dog lymphoma treatment · doxorubicin for dogs · dog cancer survival rates
Abstract
Abstarct Fifty-five dogs with lymphoma were treated using a doxorubicin-based sequential combination chemotherapy protocol. Complete response, partial response, and no response were seen in 46, 4, and 5 dogs, respectively. The overall median remission duration and survival times were 36 and 51 weeks, respectively. Age, sex, weight, World Health Organization stage, World Health Organization substage (i.e., a = not ill, b = ill), serum calcium concentration, blood urea nitrogen concentration, breed, and protocol alteration secondary to toxicity were evaluated for prognostic significance. Univariate analysis of prognostic factors identified sex, World Health Organization substage, and serum calcium as statistically significant (P≤ .05) variables for both survival and remission duration. Upon multivariate analysis, only substage (P= .036) was a significant prognostic factor for remission duration, whereas, both substage (P= .006) and sex (P= .005) were significant prognostic factors for survival. (Journal of Veterinary Internal Medicine 1993; 7:289–295. Copyright © 1993 by the American College of Veterinary Internal Medicine.)
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Search related cases →Original publication on Crossref: https://doi.org/10.1111/j.1939-1676.1993.tb01021.x