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Peer-reviewed veterinary case report

Infections linked to chronic mouth inflammation in cats

By Quimby, Jessica M. et al.·Published in Journal of Feline Medicine and Surgery·2008·College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 300 West Drake Road, Fort Collins, CO 80523, USA, United States·View original on Crossref

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Original publication title: Evaluation of the association of Bartonella species, feline herpesvirus 1, feline calicivirus, feline leukemia virus and feline immunodeficiency virus with chronic feline gingivostomatitis

Species:
cat

Plain-English summary

Nine cats with chronic gingivostomatitis (GS), which causes painful inflammation in the mouth, were examined to see if certain viruses or bacteria were responsible for their condition. The cats lived together, had been exposed to fleas, and were vaccinated. Tests for feline leukemia virus and other infectious agents showed no connection to the presence of GS. Ultimately, the study found that these infections did not appear to cause the oral discomfort seen in the affected cats.

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Abstract

Gingivostomatitis (GS) is a significant condition in cats because of oral discomfort and associated periodontal disease. Several infectious agents have been associated with the presence of GS, but a causal relationship is unclear. The cats in this study were housed together, had a history of flea exposure, and were vaccinated with a modified live FVRCP product. There were nine cats with active GS and 36 unaffected cats at the time of sample collection. Serum was tested for feline leukemia virus (FeLV) antigen and antibodies against feline immunodeficiency virus, feline calicivirus (FCV), feline herpesvirus 1 (FHV-1), and Bartonella species (enzyme-linked immunosorbent assay and Western blot immunoassay). PCR assays for Bartonella species and FHV-1 and a reverse transcriptase PCR assay for FCV were performed on blood and throat swabs. All cats were negative for FeLV. Assay results failed to correlate to the presence of GS in the group of cats studied.

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Original publication on Crossref: https://doi.org/10.1016/j.jfms.2007.05.007