Peer-reviewed veterinary case report
Vincristine treatment raises platelet counts in dogs with lymphoma
By Campbell, O et al.·Published in The Journal of small animal practice·2019·Department of Small Animal Clinical Sciences, Canada·View original on PubMed →
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Original publication title: Evaluation of the effect of vincristine on platelet count in dogs with lymphoma.
- Species:
- dog
Plain-English summary
A group of dogs with lymphoma (a type of cancer) were treated with vincristine, a chemotherapy drug, to see how it affected their platelet counts. After treatment, the dogs showed an increase in their platelet counts, and fewer dogs had low platelet levels (thrombocytopenia). This suggests that vincristine can be safely given to dogs with lymphoma even if they have low platelets, helping improve their overall health.
People also search for: dog lymphoma treatment · vincristine for dogs · low platelet count in dogs
Abstract
OBJECTIVES: To determine the effect of vincristine administration on the platelet count, platelet morphology and incidence of thrombocytopenia in dogs diagnosed with lymphoma. MATERIAL AND METHODS: Medical records of 59 dogs with lymphoma receiving vincristine sulphate were reviewed retrospectively. RESULTS: Following vincristine administration the platelet count was higher and the number of thrombocytopenic patients was lower. No difference was found in the number of dogs with enlarged and elliptical platelets following vincristine treatment. CLINICAL SIGNIFICANCE: Vincristine administration increases platelet counts in dogs with lymphoma. It is not contra-indicated to administer vincristine to dogs with lymphoma that are thrombocytopenic.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31737905/