Peer-reviewed veterinary case report
Vaccinated adult dogs caught canine parvovirus type 2c infection
By Decaro, Nicola et al.·Published in The new microbiologica·2008·Department of Animal Health and Well-being, Italy·View original on PubMed →
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Original publication title: Evidence for immunisation failure in vaccinated adult dogs infected with canine parvovirus type 2c.
- Species:
- dog
Plain-English summary
A group of vaccinated adult dogs in a breeding kennel in Italy became infected with a strain of canine parvovirus (CPV-2c), despite having received their vaccinations. Eleven dogs, aged between 6 months and 2.5 years, showed symptoms of the disease, and testing confirmed the infection. Tragically, one 20-month-old pregnant Bernese mountain dog died from the infection. This situation raises concerns about the effectiveness of current vaccines against new variants of the virus, highlighting the need for updated vaccines that can better protect dogs from these strains.
People also search for: vaccinated dog parvovirus infection · canine parvovirus symptoms · Bernese mountain dog parvovirus treatment
Abstract
An outbreak of canine parvovirus type 2c (CPV-2c) infection in vaccinated adult dogs is reported. The disease occurred in a breeding kennel in Italy and affected 11 dogs aged between 6 months and 2.5 years, that had been repeatedly administered vaccines containing a type 2 (old type) CPV strain. CPV infection was demonstrated in all diseased dogs by an immunochromatographic test. A CPV strain was isolated from the intestinal content of a 20-month-old pregnant Bernese mountain bitch that underwent a fatal outcome. The strain was characterised as CPV-2c by means of real-time PCR assays using minor groove binder probes. The present report provides further concerns about the real efficacy of type 2-based vaccines against the antigenic variants of CPV and stresses the need for developing new vaccines prepared with the variants currently circulating in the dog population.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18437851/