Peer-reviewed veterinary case report
Cancer prevention in dogs using a special supplement with antioxidants
By Kondratyuk, Tamara P et al.·Published in Scientific reports·2016·Department of Pharmaceutical Sciences, United States·View original on PubMed →
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Original publication title: Evidence supporting the conceptual framework of cancer chemoprevention in canines.
- Species:
- dog
Plain-English summary
A study looked at how a special dog biscuit containing ingredients like resveratrol and curcumin might help prevent cancer in dogs. While the biscuits didn't change the overall DNA damage in the dogs' blood, they did reduce damage caused by hydrogen peroxide, which is a type of oxidative stress. The dogs' blood tests remained normal, suggesting the biscuits were safe to eat. This research supports the idea that certain dietary supplements could help improve the health of dogs and potentially prevent cancer.
People also search for: dog cancer prevention diet · supplements for dog health · what can I give my dog to prevent cancer
Abstract
As with human beings, dogs suffer from the consequences of cancer. We investigated the potential of a formulation comprised of resveratrol, ellagic acid, genistein, curcumin and quercetin to modulate biomarkers indicative of disease prevention. Dog biscuits were evaluated for palatability and ability to deliver the chemopreventive agents. The extent of endogenous DNA damage in peripheral blood lymphocytes from dogs given the dietary supplement or placebo showed no change. However, H2O2-inducible DNA damage was significantly decreased after consumption of the supplement. The expression of 11 of 84 genes related to oxidative stress was altered. Hematological parameters remained in the reference range. The concept of chemoprevention for the explicit benefit of the canine is compelling since dogs are an important part of our culture. Our results establish a proof-of-principle and provide a framework for improving the health and well-being of "man's best friend".
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27216246/