Peer-reviewed veterinary case report
Changes in blood tests during weight loss in obese Beagle dogs
By Diez, M et al.·Published in Journal of animal physiology and animal nutrition·2004·Animal Production Department·View original on PubMed →
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Original publication title: Evolution of blood parameters during weight loss in experimental obese Beagle dogs.
- Species:
- dog
Plain-English summary
Eight obese Beagle dogs were put on either a high-protein diet or a high-fiber diet to help them lose weight and improve their health. Over 12 to 26 weeks, both diets helped lower triglycerides and cholesterol levels, but the high-protein diet was more effective. While the dogs lost weight, their levels of certain hormones and other blood parameters remained stable, except for a significant drop in a thyroid hormone (fT4). Overall, the high-protein diet was found to be a safe option for weight loss in these dogs.
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Abstract
The effects of weight loss on hormonal and biochemical blood parameters were measured monthly [carnitine, creatinine, urea, free T4 (fT4), total T4 (TT4), plasma alkaline phosphatases (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), potassium and total proteins] or bimonthly [cholesterol, triglycerides, non-esterified fatty acids (NEFA), insulin-like growth factor I (IGF-I), glucose, insulin] in eight obese Beagles dogs fed either a high protein dry diet, DP (crude protein 47.5%, on dry matter basis) or a commercial high fibre diet, HF (crude protein 23.8%, crude fibre 23.3%). The dogs were allotted to two groups according to sex and body weight (BW) and they were respectively fed with the DP or the control HF diet during 12-26 weeks, until they reach their optimal BW. The plasma basal triglycerides and cholesterol concentrations were decreased by the two diets but the difference was only significant for the DP diet. The plasma mean NEFA concentration increased regularly over the period with the HF diet, without significant difference between the two diets. No effect of diet or weight loss was observed on plasma carnitine, urea, creatinine, ALP, AST, ALT, potassium, TT4, FT4, IGF-I, glucose and insulin. Weight loss induced a decrease in fT4 plasma concentration (p < 0.001). The high protein diet allowed a safe weight loss.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15059242/