Peer-reviewed veterinary case report
Fever and swollen lymph nodes in dogs with acute ehrlichiosis
By de Castro, Márcio Botelho et al.·Published in Veterinary parasitology·2004·Department of Veterinary Pathology, Brazil·View original on PubMed →
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Original publication title: Experimental acute canine monocytic ehrlichiosis: clinicopathological and immunopathological findings.
- Species:
- dog
Plain-English summary
A group of dogs infected with Ehrlichia canis, a type of bacteria that can cause serious illness, developed high fevers and other concerning symptoms about 10 to 14 days after exposure. These dogs showed signs like pale gums, swollen lymph nodes, and fluid buildup in their bodies. Tests revealed changes in their immune response and damage to organs like the liver and kidneys. Unfortunately, the study focused on the disease's effects rather than treatment, so it’s unclear how these dogs were managed or if they recovered. If your dog shows similar symptoms, it’s important to consult your veterinarian for proper diagnosis and treatment.
People also search for: dog fever symptoms · Ehrlichia canis treatment · swollen lymph nodes in dogs · dog kidney problems · dog immune system issues
Abstract
Clinical signs, humoral and cellular immune responses, and microscopic and gross tissue alterations resulting from acute experimental Ehrlichia canis infection in dogs were studied. Four dogs were inoculated with E. canis and four were used as uninfected controls. After a 10-14-day incubation period, infected dogs developed pyrexia up to 41 degrees C for 6-8 days. Antibody titers to E. canis antigen were demonstrable in all inoculated dogs at 30 days post-infection. Necropsy of infected animals revealed pale mucous membranes, generalized lymphadenopathy, splenomegaly, edema and ascites. Microcopically, the main lesions were: lymphoreticular hyperplasia in cortical areas of lymph nodes and spleenic white pulp, periportal accumulation of mononuclear cells and centrolobular fatty degeneration of the liver. Kidneys presented with glomerulonephritis characterized by interstitial mononuclear infiltration. Immunophenotyping of lymphocytes from lymph nodes and spleen sections displayed alterations in IgG, IgM, CD3+ and CD8+ cells population in infected dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15036578/