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Peer-reviewed veterinary case report

Dog with bone cancer tumor in jaw salivary gland and lung spread

By Thomsen, B V & Myers, R K·Published in Veterinary pathology·1999·Department of Veterinary Pathology, United States·View original on PubMed

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Original publication title: Extraskeletal osteosarcoma of the mandibular salivary gland in a dog.

Species:
dog
OsteosarcomaMovement & jointsDogs

Plain-English summary

A 14-year-old spayed female shepherd/collie mix had a large mass removed from below her right ear, which turned out to be an aggressive type of bone cancer called osteosarcoma. Unfortunately, a month after surgery, the mass returned and had spread to her lungs, lymph nodes, and kidneys. This case highlights the seriousness of tumors in the salivary glands, as most are found to be cancerous. Sadly, the prognosis for this dog was poor due to the aggressive nature of the cancer and its spread.

People also search for: dog ear mass · osteosarcoma in dogs · dog salivary gland tumor treatment · dog cancer prognosis · shepherd collie cancer symptoms

Abstract

A 14-year-old spayed female shepherd/collie crossbred dog had a 6 x 4-cm mass excised from below the right ear. The partially encapsulated, neoplastic mass had a necrotic core and was embedded in the mandibular salivary gland. Histologically, the mass was composed of numerous multinucleate giant cells and large, oval, pleomorphic cells that produced osteoid. Neoplastic cells were immunoreactive for vimentin and actin but not for keratin, desmin, or S-100 protein. At postmortem examination 1 month later, an 11-cm spherical mass had recurred at the surgical site, and there were metastatic nodules in the lungs, ipsilateral mandibular lymph nodes, and kidney. The tumor was diagnosed as an osteosarcoma of the mandibular salivary gland with pulmonary, lymphatic, and renal metastasis. In addition, a 17-year survey of canine salivary-gland neoplasms revealed that most were adenocarcinomas or carcinomas.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9921759/