Peer-reviewed veterinary case report
What affects remission and survival in dogs with lymphoma
By Baskin, C R et al.·Published in Journal of the American Animal Hospital Association·2000·Department of Veterinary Clinical Sciences and Comprehensive Cancer Center, United States·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Factors influencing first remission and survival in 145 dogs with lymphoma: a retrospective study.
- Species:
- dog
Plain-English summary
A group of 145 dogs diagnosed with lymphoma (a type of cancer) was studied to understand what affects their chances of recovery and survival. Dogs with certain long-term inflammatory diseases were more likely to have their cancer return. However, those with advanced lymphoma or treated with a specific chemotherapy protocol (CHOP) had a better chance of staying in remission. Unfortunately, dogs that showed worsening symptoms after initial treatment or experienced gastrointestinal side effects had a higher risk of passing away. This information can help veterinarians tailor treatment plans for dogs with lymphoma.
Abstract
Records of 145 dogs diagnosed with lymphoma were reviewed to evaluate for factors influencing duration of remission and survival. Dogs with histories of certain chronic inflammatory diseases were 3.23 times more likely to relapse (relative risk, 3.23) than the overall population. Dogs with World Health Organization (WHO) stage IV lymphoma or those treated with a protocol containing cyclophosphamide, doxorubicin, vincristine, prednisone, and sulfatrimethoprim (CHOP) had lower relative risks of relapse (0.32 and 0.085, respectively). Progressive disease after induction, gastrointestinal toxicity from induction, and clinical signs (i.e., substage b lymphoma) were associated with higher relative risks of death (3.5, 2.64, and 2.02, respectively).
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10997515/