Peer-reviewed veterinary case report
Kidney disease in 8 related Bracchi Italiani dogs (2012-2019)
By Inman, Amanda L et al.·Published in Journal of the American Veterinary Medical Association·2021·From the Department of Small Animal Clinical Sciences, United States·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Familial nephropathy in Bracchi Italiani: 8 cases (2012-2019).
- Species:
- dog
Plain-English summary
Eight Bracchi Italiani dogs were diagnosed with kidney disease, showing symptoms like loss of appetite and protein in their urine. Unfortunately, most of these dogs had serious conditions like glomerular amyloidosis, which is a type of kidney damage. Once they started showing signs of illness, they were euthanized about 75 days later on average. This study highlights that if a young or middle-aged Bracchi Italiano has protein in their urine, it could indicate a hereditary kidney problem, and the outlook is often not good once symptoms appear.
People also search for: Bracco Italiano kidney disease symptoms · dog loss of appetite causes · hereditary nephropathy in dogs
Abstract
OBJECTIVE: To characterize the signalment, clinical signs, clinical pathological and histologic findings, and outcome in 8 related Bracchi Italiani with proteinuric kidney disease. ANIMALS: 8 client-owned Bracchi Italiani. PROCEDURES: Health records submitted to the Bracco Italiano Health Foundation and the Bracco Italiano Club of America between 2012 and 2019 were reviewed for dogs with evidence of nephropathy for which histologic diagnoses were obtained. Pedigree, signalment, clinical signs, diagnostic test results (including microscopic examination of kidney tissue samples collected ante- or postmortem), and outcome were acquired. Results were presented as descriptive statistics. RESULTS: The most common clinical sign in affected dogs was inappetence. All dogs were proteinuric, and 4 dogs were azotemic. Seven dogs developed clinical signs of kidney disease and were euthanized a median of 75 days postdiagnosis. Six dogs had glomerular amyloidosis, and 1 dog each had nephrosclerosis and nonamyloidotic fibrillar glomerulopathy. CONCLUSIONS AND CLINICAL RELEVANCE: Results indicated that the clinical presentation may vary in affected dogs, and proteinuria in young or middle-aged Bracchi Italiani should raise the concern for hereditary nephropathy. Prognosis is likely poor once clinical signs are noted.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34757934/