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Peer-reviewed veterinary case report

Fanconi syndrome causing excessive thirst and urination in young

By Bommer, Nick X et al.·Published in Journal of the American Animal Hospital Association·2018·From the Royal (Dick) School of Veterinary Studies, United Kingdom·View original on PubMed

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Original publication title: Fanconi Syndrome in Irish Wolfhound Siblings.

Species:
dog

Plain-English summary

Three young male Irish Wolfhound brothers were brought to the vet because they were drinking a lot of water and urinating frequently. Tests showed they had sugar and amino acids in their urine, low potassium levels, and metabolic acidosis, which are signs of Fanconi syndrome, a kidney disorder. The vets treated them with a special supplement plan that has worked for other breeds with the same condition. Thankfully, these dogs did not have the bone deformities that can sometimes occur with this syndrome, and their treatment was tailored specifically for them since this condition is rare in Irish Wolfhounds.

People also search for: Irish Wolfhound kidney disease · Fanconi syndrome treatment for dogs · why is my dog drinking so much water

Abstract

Three juvenile male Irish wolfhound littermates presented with marked polyuria and polydipsia. The four female siblings were apparently unaffected. Diagnostic testing revealed glucosuria with normoglycemia, generalized aminoaciduria, hypokalemia and metabolic acidosis consistent with Fanconi syndrome. Renal ultrasonographic and histologic findings are presented. Cases were managed with a supplementation regimen based on a treatment protocol for Fanconi syndrome in basenjis. These dogs did not have angular limb deformities as documented previously in juvenile canine siblings with Fanconi syndrome. Fanconi syndrome has not been previously described in Irish wolfhound siblings.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29558216/