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Peer-reviewed veterinary case report

Fatal SV40-associated pneumonia and nephropathy following renal allotransplantation in rhesus macaque.

Journal:
Journal of medical primatology
Year:
2018
Authors:
Song, M et al.
Affiliation:
Department of Surgery · United States

Abstract

Recrudescence of latent and dormant viruses may lead to overwhelming viremia in immunosuppressed hosts. In immunocompromised hosts, Simian virus 40 (SV40) reactivation is known to cause nephritis and demyelinating central nervous system disease. Here, we report SV40 viremia leading to fatal interstitial pneumonia in an immunosuppressed host following renal allotransplantation.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/28671309/