Peer-reviewed veterinary case report
Dog died from systemic Ochroconis gallopavum fungal infection
By Singh, K et al.·Published in Veterinary pathology·2006·Department of Veterinary Pathobiology, United States·View original on PubMed →
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Original publication title: Fatal systemic phaeohyphomycosis caused by Ochroconis gallopavum in a dog (Canis familaris).
- Species:
- dog
Plain-English summary
A 5-year-old Shetland Sheepdog was brought to the vet because it was weak, had trouble walking, and occasionally had seizures. The dog had been on prednisone for inflammatory bowel disease and had a previous infection with Ehrlichia canis. Despite treatment, the dog continued to decline and sadly passed away. A post-mortem examination revealed severe infections in multiple organs caused by a type of fungus called Ochroconis gallopavum. Unfortunately, the dog did not recover from this serious condition.
People also search for: dog weakness and seizures · Shetland Sheepdog fungal infection · treatment for dog anemia · dog inflammatory bowel disease symptoms
Abstract
A 5-year-old Shetland Sheepdog was presented with a history of weakness, ataxia, anemia, thrombocytopenia, and occasional seizures. The dog had been treated for 6 months with prednisone for inflammatory bowel disease. A positive titer for Ehrlichia canis was detected 6 months before referral. The initial physical examination revealed a weak, laterally recumbent dog with pale mucous membranes. Neurologic examination revealed multiple neurologic deficits. A complete blood cell count (CBC) revealed normochromic, normocytic, nonregenerative anemia; lymphopenia; thrombocytopenia; and neutrophilic and monocytic leukocytosis. Urinalysis revealed proteinuria, with a specific gravity of 1.045. The dog was unresponsive to treatment and died. At necropsy, there was severe serofibrinous peritonitis and pleuritis, with randomly scattered dark brown necrotic foci present in multiple organs, including liver, spleen, kidney, and pancreatic lymph node. Histologically, there were extensive regions of parenchymal necrosis surrounded by neutrophils admixed with epithelioid macrophages, lymphocytes, and pigmented fungal organisms. Numerous brown, 2 to 6 microm in diameter, septate, branching hyphae, subsequently identified as Ochroconis gallopavum (formerly Dactylaria constricta var. gallopava), were observed.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17099156/