Peer-reviewed veterinary case report
Cats with high-grade gut lymphoma treated by surgery and CHOP chemo
By Gouldin, E D et al.·Published in Veterinary and comparative oncology·2017·Department of Surgery, United States·View original on PubMed →
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Original publication title: Feline discrete high-grade gastrointestinal lymphoma treated with surgical resection and adjuvant CHOP-based chemotherapy: retrospective study of 20 cases.
- Species:
- cat
Plain-English summary
A group of cats diagnosed with high-grade gastrointestinal lymphoma underwent surgery to remove the affected part of their intestines, followed by chemotherapy treatment. Out of the 20 cats treated, three were still alive after the study period, with an average survival time of about 417 days. The results suggest that this combination of surgery and chemotherapy can help improve survival rates for cats with this type of cancer. If your cat is diagnosed with gastrointestinal lymphoma, discussing surgical options followed by chemotherapy with your veterinarian may be beneficial.
People also search for: cat lymphoma treatment · gastrointestinal cancer in cats · cat surgery for cancer · chemotherapy for cats with lymphoma
Abstract
The aim of this retrospective study was to evaluate the outcome of cats treated with surgical intervention for a discrete intermediate-/high-grade gastrointestinal lymphoma prior to CHOP-based chemotherapy. Variables including sex, breed, haematocrit, white blood cell count, serum albumin concentration, clinical stage of disease, gastrointestinal obstruction and peritonitis were assessed for their effect on survival. Twenty cats met the inclusion criteria with three cats still alive at the time of data analysis. The overall median survival time (MST) was 417 days (range: 12-2962 days). The disease-free interval (DFI) was 357 days (range: 0-1585 days) with six cats still deemed in remission prior to death. Only clinical stage had a significant effect on both MST and DFI. Cats with discrete intermediate/high-grade gastrointestinal lymphoma that undergo surgical resection followed by adjuvant CHOP chemotherapy may achieve acceptable overall survival times.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26333999/