Peer-reviewed veterinary case report
Eye toxoplasmosis in cats: diagnosis and treatment results from 60
By Ali, K M et al.·Published in Polish journal of veterinary sciences·2021·Department of Surgery·View original on PubMed →
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Original publication title: Feline ocular toxoplasmosis: seroprevalence, diagnosis and treatment outcome of 60 clinical cases.
- Species:
- cat
Plain-English summary
A group of 105 cats with eye problems was examined for a common infection called toxoplasmosis. Out of these, 60 cats tested positive for Toxoplasma gondii, with many showing signs like inflammation in the front part of the eye. The cats were treated with a combination of topical and systemic medications, and about half of them responded well to treatment, with nearly 47% showing complete recovery. If your cat has eye issues without a clear cause, it might be worth asking your vet about testing for toxoplasmosis and potential treatments.
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Abstract
Toxoplasmosis is one of the most important protozoa zoonotic diseases worldwide. The present study describes the clinical, seroprevalence findings with ocular toxoplasmosis and the outcome of medicinal treatment of these cats. This study was carried out on 105 cats with various ocular signs, no historical evidence of ocular trauma or drug/vaccine exposure for at least 3 months prior to admission, and without clinical or laboratory evidence of other systemic diseases. Complete case history, physical and ophthalmic examinations were carried out. The seroprevalence of Toxoplasma gondii antibodies was determined using the Toxoplasma Ab Rapid Test and Enzyme Linked Immunosorbent Assay. Out of 105 examined cats with ocular lesions, 60 cats representing 57.14% were seropositive to T. gondii. Out of these 60 cats, 15 cats (25%) had bilateral ocular abnormalities, 25 cats (41.67%) had right-sided ocular disease, and 20 cats (33.33%) had left-sided ocular disease. There were 38 cats (63.33%) with anterior uveitis, 12 cats (20%) with posterior segment involvement, 5 cats (8.33%) with anterior uveitis and anterior chamber abnormalities, 3 cats (5%) with corneal abnormalities and 2 cats (3.34%) with anterior uveitis with concurrent corneal involvement. There was a significant difference in the index values of IgM and IgG between seropositive and seronegative cats with T. gondii antibodies (p⟨0.05). There was no significant difference between the different ages, genders and breeds of cats with seroprevalence of T. gondii antibodies as well as between the age and total number of cats with seropositive and seronegative T. gondii. Out of 60 treated cats, 28 cats (46.7%), 25 cats (41.7%) and 7 cats (11.6%) showed complete, partial and poor response to treatment, respectively. In conclusion, cats showing ocular signs without obvious etiology should be examined serologically for toxoplasmosis and the seropositive cats should be treated with both specific topical and systemic treatments.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33847093/