Peer-reviewed veterinary case report
Cat with fibrosarcoma tumors and spread despite negative FeLV test
By White, Mary E et al.·Published in Veterinary clinical pathology·2020·Department of Veterinary Biosciences, United States·View original on PubMed →
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Original publication title: Fibrosarcoma with sarcomatosis and metastasis in a FeLV-negative cat.
- Species:
- cat
Plain-English summary
A 6-year-old spayed female mixed shorthair cat was brought to the emergency vet for high calcium levels, a mass in her right eye, and several masses in her chest and abdomen. Tests showed that these masses were likely fibrosarcoma, a type of cancer, but the cat was unfortunately euthanized before treatment could be initiated. The examination confirmed that she had widespread fibrosarcoma, which is a rare but serious condition in cats. This case is notable because it was the first reported instance of this type of cancer in a cat that tested negative for feline leukemia virus (FeLV).
People also search for: cat eye mass · cat cancer treatment · fibrosarcoma in cats · high calcium levels in cats · FeLV-negative cat cancer
Abstract
A 6-year-old, spayed female, mixed shorthair cat presented to the emergency service at The Ohio State University Veterinary Medical Center for evaluation of hypercalcemia, a right eye mass, and multiple intrathoracic and intra-abdominal masses. Cytologic evaluation of one of the abdominal masses revealed a uniform population of large, anaplastic mesenchymal cells found individually, in loose aggregates, and occasionally associated with pink, extracellular matrix. The cytology was consistent with a malignant mesenchymal neoplasm, with primary consideration given to fibrosarcoma and hemangiosarcoma. The cat was euthanized and histopathology confirmed disseminated fibrosarcoma. Fibrosarcoma comprises 12%-41% of feline cutaneous tumors and affects cats at a mean age of 9.6 years. Three manifestations of fibrosarcoma predominate in cats: spontaneous solitary fibrosarcoma, vaccine-induced/injection site fibrosarcoma, and oncogene-induced (FSV) fibrosarcoma. The history, signalment, and results from diagnostics performed did not support solitary fibrosarcoma or injection-induced sarcoma. Although some criteria fit with virally induced fibrosarcoma, such as age and the presence of multiple fibrosarcomas, the neoplastic population was negative for FeLV IHC. The presence of fibrosarcomas throughout the pleural and peritoneal cavity was most compatible with sarcomatosis and the distant metastasis of an unidentified primary neoplasm. To the authors' knowledge, this is the first reported case of sarcomatosis in a FeLV-negative cat.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32232857/