Peer-reviewed veterinary case report
Dog develops fibrosarcoma tumor at microchip implant site
By Vascellari, M et al.·Published in Veterinary pathology·2006·Istituto Zooprofilattico Sperimentale delle Venezie, Italy·View original on PubMed →
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Original publication title: Fibrosarcoma with typical features of postinjection sarcoma at site of microchip implant in a dog: histologic and immunohistochemical study.
- Species:
- dog
Plain-English summary
A 9-year-old male French Bulldog was brought in because of a lump under the skin where his microchip was implanted. Tests showed that the lump was a high-grade fibrosarcoma, a type of cancer that can develop at injection sites. The tumor was aggressive and showed signs of necrosis, meaning some parts were dying off. Unfortunately, this type of cancer can be serious, and treatment options may vary. It's important for pet owners to monitor any unusual lumps or bumps, especially near injection sites, and consult their veterinarian for further evaluation and treatment options.
People also search for: dog lump near microchip · French Bulldog fibrosarcoma · dog cancer treatment options
Abstract
A 9-year-old, male French Bulldog was examined for a subcutaneous mass located at the site of a microchip implant. Cytologic examination of the mass was suggestive of a malignant mesenchymal neoplasm. Histologically, the mass was confirmed as a high-grade infiltrative fibrosarcoma, with multifocal necrosis and peripheral lymphoid aggregates. By immunohistochemistry, the sample was investigated for vimentin, smooth-muscle actin (SMA), CD3, CD79alpha, and CD18. All the neoplastic cells were positive for vimentin. Scattered cells at the periphery of the lesion were also positive for SMA, highlighting a myofibroblastic phenotype. The lymphoid cells were positive for CD18 and CD3. No aluminum deposits were detected by the aurintricarboxylic acid method. A diagnosis of fibrosarcoma morphologically similar to feline postinjection sarcomas was made. Fibrosarcomas at the site of injections have been reported in dogs and ferrets. Furthermore, neoplastic growth at the site of microchip implant in dog and laboratory rodents has been described.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16846997/