Peer-reviewed veterinary case report
First complete genome sequence and molecular characterization of Canine morbillivirus isolated in Central Brazil.
- Journal:
- Scientific reports
- Year:
- 2021
- Authors:
- da Costa, Vivaldo Gomes et al.
- Affiliation:
- Department of Cell Biology · Brazil
- Species:
- dog
Abstract
The Brazilian regions are still highly endemic areas for Canine morbillivirus [canine distemper virus (CDV)]. However, little is known regarding the genetic variability of the strain circulating in several Brazilian regions. Here, we report the first full-length genome and molecular characterization of CDV isolated from domestic dogs in the Brazilian Center-West region. Sequence alignment and phylogenetic analyses based on deduced amino acid and nucleotide sequences showed that the isolated strain is characterized as the South America-I/Europe genotype. However, it segregates into a CDV subgenotype branch. Interestingly, both H and F proteins have a gain of a potential N-glycosylation sites compared to the Onderstepoort vaccine strain. Therefore, this study provides a reference to further understand the epidemic and molecular characteristics of the CDV in Brazil.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/34158515/