Peer-reviewed veterinary case report
Treatment of leishmaniasis in a pregnant dog with meglumine
By Spada, Eva et al.·Published in Journal of the American Animal Hospital Association·2011·Department of Veterinary Clinical Science, Italy·View original on PubMed →
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Original publication title: First report of the use of meglumine antimoniate for treatment of canine leishmaniasis in a pregnant dog.
- Species:
- dog
Plain-English summary
A 4-year-old female dog with leishmaniasis (a parasitic infection) was treated with meglumine antimoniate while she was pregnant. The treatment improved her condition, and she had a normal pregnancy and delivery. Although three of her puppies sadly died shortly after birth, the two surviving puppies showed no signs of the infection as they grew up. This case suggests that using meglumine antimoniate during pregnancy might help prevent passing the infection to the puppies.
People also search for: dog leishmaniasis treatment · pregnant dog infection · puppy health after mother sick · meglumine antimoniate for dogs
Abstract
Canine leishmaniasis during pregnancy is rarely reported, even in countries where the infection in dogs is endemic. The authors report a case of a 4 yr old bitch with leishmaniasis treated with meglumine antimoniate during pregnancy. The pregnancy and delivery were normal and the bitch presented improvement of the infection during treatment. Three puppies died within 2 days of birth and tested negative via real-time PCR for L. infantum. The two surviving puppies were followed clinically, serologically, and by real-time PCR until 1 yr of age with no evidence of congenital leishmaniasis. L. infantum DNA was detected with real-time PCR analysis of uterine tissue from the bitch at the time of ovariohysterectomy. PCR analysis was performed after an ovariohysterectomy of the bitch that was performed two months after parturition. Meglumine antimoniate use in the pregnant bitch may have prevented vertical transmission of leishmaniasis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21164165/