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Peer-reviewed veterinary case report

Four-fraction radiation therapy for macroscopic soft tissue sarcomas in 16 dogs.

Journal:
Journal of the American Animal Hospital Association
Year:
2008
Authors:
Lawrence, Jessica et al.
Affiliation:
School of Veterinary Medicine · United States
Species:
dog

Abstract

A retrospective study of 16 dogs with macroscopic soft tissue sarcomas was performed to evaluate response to a four-fraction radiotherapy protocol (prescribed dose of 32 Gy). Radiation was well tolerated with minimal side effects. The overall response rate was 50%, with seven partial responses and one complete response. The median time to progression was 155 days, and the median survival time was 309 days. Coarsely fractionated radiation therapy may be a reasonable palliative option for dogs with unresectable soft tissue sarcomas, although the response is relatively short-lived.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/18451067/