Peer-reviewed veterinary case report
How often do dogs with chronic kidney disease have bacteria in their
By Lamoureux, Anaïs et al.·Published in Journal of veterinary internal medicine·2019·Dé, France·View original on PubMed →
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Original publication title: Frequency of bacteriuria in dogs with chronic kidney disease: A retrospective study of 201 cases.
- Species:
- dog
Plain-English summary
A study found that 32% of dogs with chronic kidney disease (CKD) had a positive urine culture, meaning bacteria were present in their urine. Interestingly, most of these dogs showed no signs of a urinary tract infection, which can include symptoms like frequent urination or straining to urinate. Female dogs and those with certain urine characteristics were more likely to test positive for bacteria. This suggests that regular urine testing might be helpful for dogs with CKD, even if they seem fine. However, more research is needed to understand the significance of these findings.
People also search for: dog chronic kidney disease symptoms · dog urine culture results · why is my dog urinating frequently · dog urinary tract infection signs · treatment for dog kidney disease
Abstract
BACKGROUND: Studies have shown an increased prevalence of positive urine culture (PUC) in cats with chronic kidney disease (CKD); no information is available in dogs. OBJECTIVES: To document the PUC frequency in a cohort of dogs with CKD, determine risk factors for PUC, and identify associations between clinicopathologic data and PUC. ANIMALS: Two hundred one client-owned dogs with CKD. METHODS: Retrospective, observational study. Dogs recruited from 2 veterinary teaching hospitals were included if they were diagnosed with CKD and had a culture performed on urine collected by cystocentesis. The PUC frequency was calculated, multivariate analysis was performed to identify risk factors, and associations with clinicopathologic data were investigated. RESULTS: Sixty-five dogs (32%) with CKD had PUC, including 8 (28%) in International Renal Interest Society (IRIS) stage 1; only 8% showed signs of a urinary tract infection. Escherichia coli was the most common isolate (67%). A PUC was more likely in females (odds ratio [OR], 3.22; 95% confidence interval [CI], 1.67-6.37; P < .001) than males and in dogs with isosthenuria (OR, 2.48; 95% CI, 1.24-5.03; P = .01) than in dogs with urine-specific gravity 1.013-1.024. A positive leukocyte esterase test and microorganisms found by urine sediment analysis were significantly associated with PUC (both P < .001). CONCLUSIONS AND CLINICAL IMPORTANCE: Dogs with CKD, even IRIS stage 1, have a high frequency of PUC and most cases are asymptomatic. A urine culture could be considered in the routine evaluation of dogs with CKD, but the clinical relevance of a PUC remains unknown and needs further evaluation.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30767319/