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Peer-reviewed veterinary case report

Gastrict carcinoma with pseudohyperparathyroidism in a horse.

Journal:
The Cornell veterinarian
Year:
1978
Authors:
Meuten, D J et al.
Species:
horse

Plain-English summary

A mature stallion was brought in because he had stopped eating, was losing weight, was urinating more often, and was constipated. Tests showed he had high calcium levels, low phosphorus levels, anemia, and urine that was not concentrated. A procedure to collect fluid from his chest revealed that he had a type of cancer called squamous cell carcinoma. Sadly, during the examination after he passed away, it was confirmed that he had stomach cancer that had spread to his abdomen and chest, but there were no signs of it spreading to his bones or kidneys. Unfortunately, the treatment did not work, and the horse did not survive.

Abstract

Pseudohyperparathyroidism was diagnosed in a mature stallion presented for anorexia, weight loss, pollakiuria and constipation. Laboratory findings included hypercalcemia, hypophosphatemia, anemia and isosthenuria. Thoracocentesis indicated an exfoliating squamous cell carcinoma. At necropsy, a squamous cell carcinoma of the stomach with metastases to the abdominal and thoracic cavities was diagnosed. No osseous metastases were found. No gross or microscopic renal lesions were noted. Bone tissue showed arrested resorption, and the parathyroid gland was atrophic.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/639516/