Peer-reviewed veterinary case report
Primary Hyperparathyroidism in a Quarter Horse Mare Associated With a Chief Cell Adenoma.
- Journal:
- Journal of equine veterinary science
- Year:
- 2020
- Authors:
- Darby, Shannon et al.
- Affiliation:
- Department of Large Animal Clinical Sciences · United States
- Species:
- horse
Plain-English summary
This case involves a 12-year-old Quarter Horse mare diagnosed with primary hyperparathyroidism, a rare condition where the parathyroid glands produce too much hormone, leading to imbalances in calcium and other electrolytes. The mare had a growth called a chief cell adenoma on one of her parathyroid glands, which was confirmed using a special test. She underwent surgery to remove the adenoma, and her treatment included medical management to address the hormone and electrolyte issues. This case is significant because it highlights a new way to confirm this type of growth in horses. The treatment was successful in managing her condition.
Abstract
Primary hyperparathyroidism is rare in large animal species, and little is known regarding its pathophysiology, endocrine and electrolyte derangements, diagnosis, medical management, and prognosis. This report describes the clinicopathologic diagnosis of a parathyroid (PT) gland chief cell adenoma in a 12-year-old Quarter Horse mare, including PT hormone (PTH) and electrolyte disarrangements associated with the neoplasia, the surgical removal of the adenoma, and medical management of the case. This report also describes for the first time the use PTH immunohistochemistry to confirm the nature of this neoplasia in a horse.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/33276927/