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Peer-reviewed veterinary case report

Genomic comparison of Mycobacterium avium subsp. paratuberculosis sheep and cattle strains by microarray hybridization.

Journal:
Journal of bacteriology
Year:
2006
Authors:
Marsh, Ian B et al.
Affiliation:
Faculty of Veterinary Science · Australia

Abstract

Microarray-based comparisons of three Mycobacterium avium subsp. paratuberculosis isolates, including one sheep strain and two cattle strains, identified three large genomic deletions in the sheep strain, totaling 29,208 bp and involving 24 open reading frames. These deletions may help explain some of the differences in pathogenicity and host specificity observed between the cattle and sheep strains of Mycobacterium avium subsp. paratuberculosis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/16513760/