Peer-reviewed veterinary case report
Giant hypertrophic gastritis (Menetrier's-like disease) in an Old English sheepdog.
- Journal:
- Journal of the American Animal Hospital Association
- Year:
- 2007
- Authors:
- Rallis, Tim S et al.
- Affiliation:
- Clinic of Companion Animal Medicine
- Species:
- dog
Plain-English summary
An 11-year-old male Old English sheepdog was taken to the vet because he had been losing weight and vomiting off and on for about a month. Tests showed he had a mass in his abdomen, low red blood cell levels, and low protein levels in his blood. Imaging revealed that his stomach wall was unusually thick with large folds, and surgery confirmed a condition called giant hypertrophic gastritis, which means his stomach lining was overgrown but not cancerous. He was treated with medications, including steroids and other drugs, but unfortunately, the improvement he experienced was only temporary.
Abstract
An 11-year-old, male Old English sheepdog was admitted for weight loss and intermittent vomiting of 1 month's duration. A cranioventral abdominal mass, anemia, hypoproteinemia, and hypoalbuminemia were the prominent abnormal findings. Imaging studies identified a remarkably thickened gastric wall with multilobulated folds protruding into the gastric lumen. Gastrotomy revealed the presence of giant cerebriform rugal folds arising from the fundus and body of the stomach. Pronounced gastric glandular hyperplasia and lack of evidence of cellular atypia were suggestive of giant hypertrophic gastritis. The dog was treated with prednisolone, cimetidine, and hyoscine butylbromide, only to experience a short-term remission.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/17339290/