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Peer-reviewed veterinary case report

Old English sheepdog with giant hypertrophic gastritis and vomiting

By Rallis, Tim S et al.·Published in Journal of the American Animal Hospital Association·2007·Clinic of Companion Animal Medicine·View original on PubMed

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Original publication title: Giant hypertrophic gastritis (Menetrier's-like disease) in an Old English sheepdog.

Species:
dog

Plain-English summary

An 11-year-old male Old English sheepdog was brought to the vet because he was losing weight and vomiting intermittently for a month. Tests showed he had a thickened stomach wall and other issues like anemia. During surgery, the vet found abnormal folds in the stomach lining, indicating a condition called giant hypertrophic gastritis. The dog was treated with medications, including prednisolone, but only experienced a short-term improvement.

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Abstract

An 11-year-old, male Old English sheepdog was admitted for weight loss and intermittent vomiting of 1 month's duration. A cranioventral abdominal mass, anemia, hypoproteinemia, and hypoalbuminemia were the prominent abnormal findings. Imaging studies identified a remarkably thickened gastric wall with multilobulated folds protruding into the gastric lumen. Gastrotomy revealed the presence of giant cerebriform rugal folds arising from the fundus and body of the stomach. Pronounced gastric glandular hyperplasia and lack of evidence of cellular atypia were suggestive of giant hypertrophic gastritis. The dog was treated with prednisolone, cimetidine, and hyoscine butylbromide, only to experience a short-term remission.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17339290/