Peer-reviewed veterinary case report
Dog with brain tumor causing seizures and circling behavior
By Sant’Ana, Fabiano J. F. de & Barros, Claudio S. L.·Published in Brazilian Journal of Veterinary Pathology·2011·View original on Crossref →
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Original publication title: Gliomatosis Cerebri in a Dog
- Species:
- dog
Plain-English summary
A 6-year-old female mixed-breed dog was brought in after showing signs of weakness, trouble coordinating her movements, circling to the right, and having seizures. Unfortunately, despite a thorough examination, no visible issues were found in her brain during the necropsy. However, further testing revealed a serious condition called gliomatosis cerebri, which involves abnormal growth of glial cells in the brain. Sadly, this condition is severe and often leads to poor outcomes, as it indicates a significant brain tumor.
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Abstract
A 6-year-old, female, mixed-breed dog was presented for necropsy with history of prostration and incoordination followed by circling to the right and seizures. There were no gross findings in the brain. Histologically, there were numerous neoplastic glial cells throughout the thalamus, midbrain, pons and medulla oblongata. Moderate multifocal lymphoplasmacytic perivascular cuffings were also present in the same areas. In addition, severe multifocal proliferation of glial cells was observed in the leptomeninge and white matter of the cerebellum. The neoplastic cells observed in the brain stem were negative for GFAP, while in the cerebellum the neoplastic glial cells were strongly labeled with GFAP and vimentin. Based on the histopathological findings and on the immunohistochemical results, a diagnosis of gliomatosis cerebri was made.
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Search related cases →Original publication on Crossref: https://doi.org/10.24070/bjvp.1983-0246.004011