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Peer-reviewed veterinary case report

Dog with kidney inflammation linked to canine adenovirus

By Sánchez-Cordón, P J et al.·Published in Journal of veterinary medicine. B, Infectious diseases and veterinary public health·2002·Departamento Anatom&#xed, Spain·View original on PubMed

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Original publication title: Glomerulonephritis associated with simultaneous canine adenovirus-1 and Dirofilaria immitis infection in a dog.

Species:
dog

Plain-English summary

A 2-year-old dog was diagnosed with kidney disease (glomerulonephritis) after showing signs of illness related to both a viral infection (canine adenovirus-1) and heartworm (Dirofilaria immitis). The dog's condition involved abnormal immune deposits in the kidneys, but the exact cause of these deposits wasn't clearly linked to the viral infection or the heartworm. Treatment details are not specified, but managing both infections is crucial for recovery. It's important for pet owners to be aware of the signs of kidney issues and seek veterinary care if their dog shows symptoms of illness.

People also search for: dog kidney disease symptoms · heartworm treatment for dogs · canine adenovirus infection signs

Abstract

This article describes a case of glomerulonephritis and immunocomplex (IgM, IgG and C3c) deposition in the mesangium and basement membranes of a 2-year-old dog with canine viral hepatitis and dirofilariasis. The deposits observed in the mesangium were in the vicinity of cells with viral replication. However, no clear relationship was found between viral replication and the deposition of immunocomplexes in the glomerular capillary basement membranes, which may be the reason why these deposits have only been tentatively related to the concomitant infestation by Dirofilaria immitis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12121044/