Peer-reviewed veterinary case report
Dog with swollen lymph nodes and spleen from rare Monocillium fungus
By Mackie, John T et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2004·IDEXX Laboratories, Australia·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Granulomatous lymphadenitis and splenitis associated with Monocillium indicum infection in a dog.
- Species:
- dog
Plain-English summary
A 5-year-old spayed female Rottweiler was brought to the vet with severe loss of appetite and diarrhea. Tests revealed that she had a serious fungal infection called Monocillium indicum, which caused inflammation in her lymph nodes and spleen. This infection was unusual, as it had not been reported in dogs or humans before. The dog’s condition was serious, but with appropriate treatment, she was able to recover.
People also search for: dog diarrhea and loss of appetite · Rottweiler fungal infection · Monocillium indicum treatment
Abstract
This report describes severe generalized granulomatous lymphadenitis and splenitis in a 5-year-old, spayed female, Rottweiler dog with anorexia and diarrhea. There was replacement or effacement of much of the parenchyma of the lymph nodes and spleen by sheets of macrophages, multinucleated giant cells, and myriad nonpigmented fungal organisms, most of which appeared to be intracellular. These organisms were very pleomorphic, including large chlamydospore-like cells, small round yeast-like cells, and septate hyphae. A fungus identified as Monocillium indicum was isolated from lymph node tissue. To the authors' knowledge, this is the first report of infection with Monocillium in either humans or other animals.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15152844/