Peer-reviewed veterinary case report
Granulomatous meningoencephalomyelitis causing brain and spinal
By Adamo, P Filippo et al.·Published in Compendium (Yardley, PA)·2007·University of Wisconsin, United States·View original on PubMed →
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Original publication title: Granulomatous meningoencephalomyelitis in dogs.
- Species:
- dog
Plain-English summary
A dog with granulomatous meningoencephalomyelitis (GME), a serious inflammatory disease affecting the brain and spinal cord, can show symptoms like seizures, behavioral changes, and difficulty walking. If not treated, GME can be fatal. The main treatment involves high doses of glucocorticosteroids to suppress the immune response, and new therapies are being explored for better outcomes. Early diagnosis and treatment are crucial for improving the chances of recovery in affected dogs.
People also search for: dog seizures treatment · GME in dogs · dog behavior changes · glucocorticosteroids for dogs · dog walking difficulties
Abstract
Granulomatous meningoencephalomyelitis (GME) is a nonsuppurative inflammatory disease of unknown origin that affects the central nervous system of dogs. GME is characterized histologically by large perivascular cuffs of mononuclear cells in the parenchyma and meninges of the brain and spinal cord. If left untreated, it is usually fatal. Immunosuppressive doses of glucocorticosteroids have been the mainstay of treatment for GME; however, new and more effective therapies have recently been proposed. This article reviews the pathology, origin, clinical signs, therapeutic response, and outcome of GME in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18210978/