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Peer-reviewed veterinary case report

Dog with haemophagocytic syndrome and blood clotting disorder

By Stockhaus, C & Slappendel, R J·Published in The Journal of small animal practice·1998·Department of Clinical Sciences of Companion Animals, Netherlands·View original on PubMed

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Original publication title: Haemophagocytic syndrome with disseminated intravascular coagulation in a dog.

Species:
dog

Plain-English summary

A 9-year-old male Rottweiler was brought to the vet because he was weak, depressed, had lost some weight, and was experiencing recurring fevers. The vet found that his gums were pale and his spleen was enlarged. Tests showed serious blood issues, including low blood cell counts and a dangerous clotting problem. Unfortunately, despite the vet's efforts, the dog passed away just a week after being referred for treatment.

People also search for: dog weakness and fever · Rottweiler spleen problems · dog blood clotting issues · what is haemophagocytic syndrome in dogs

Abstract

Clinical signs and haematological abnormalities of haemophagocytic syndrome of unknown origin are described for a male, nine-year-old rottweiler referred because of weakness, depression, mild weight loss and relapsing fever. Mucous membranes were pale and the spleen was enlarged. Ultrasonography revealed diffuse irregular structures in the enlarged spleen, and cytological examination of multiple fine needle aspirates of the spleen demonstrated extramedullary haematopoiesis. Haematological examination revealed pancytopenia and disseminated intravascular coagulation. A bone marrow smear contained numerous marrow macrophages with a cytologically benign appearance, containing phagocytosed haematopoietic cells. The dog died one week after referral. The differential diagnosis is discussed.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9577764/