Peer-reviewed veterinary case report
Haemoplasma infection rarely causes immune anemia in UK dogs
By Warman, S M et al.·Published in The Journal of small animal practice·2010·School of Clinical Veterinary Science, United Kingdom·View original on PubMed →
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Original publication title: Haemoplasma infection is not a common cause of canine immune-mediated haemolytic anaemia in the UK.
- Species:
- dog
Plain-English summary
A group of dogs in the UK with immune-mediated hemolytic anemia (IMHA) was tested for two types of bacteria called Mycoplasma that might cause this condition. Researchers found that none of the dogs had these bacteria in their blood, suggesting that these infections are not a common cause of IMHA in dogs. This means that if your dog has IMHA, it’s unlikely to be due to a haemoplasma infection. Your veterinarian can help determine other potential causes and appropriate treatments for your dog's condition.
People also search for: dog anemia causes · immune-mediated hemolytic anemia treatment · Mycoplasma infection in dogs
Abstract
OBJECTIVE: The aim of this study was to investigate whether the two canine haemoplasma species, Mycoplasma haemocanis and "Candidatus Mycoplasma haematoparvum," are commonly associated with immune-mediated haemolytic anaemia (IMHA) in UK dogs. METHODS: Three groups of dogs were recruited to the study: anaemic dogs with primary IMHA (n=37); anaemic dogs not meeting the inclusion criteria for primary IMHA (n=77) and non-anaemic dogs (n=113). DNA was extracted from 100 μl of blood and subjected to real-time quantitative polymerase chain reaction (qPCR) assays for both species of Mycoplasma. Each assay incorporated co-amplification of canine glyceraldehyde-3-phosphate dehydrogenase (GAPDH) as an endogenous internal control. RESULTS: Canine GAPDH was successfully amplified by qPCR from all 227 canine blood samples but none contained M. haemocanis or "Candidatus M. haematoparvum" DNA. CLINICAL SIGNIFICANCE: Haemoplasma infection is uncommon in dogs in the UK and no evidence was found that these organisms act as triggers for IMHA.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21029097/