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Peer-reviewed veterinary case report

Half-body radiation treatment for dogs with lymphoma response

By Laing, Elizabeth J. et al.·Published in Journal of Veterinary Internal Medicine·1989·Departments of Clinical Studies and Pathology Ontario Veterinary College , Guelph, Ontario, Canada·View original on Crossref

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Original publication title: Half-Body Radiotherapy in the Treatment of Canine Lymphoma

Species:
dog

Plain-English summary

A group of 14 dogs with multicentric lymphoma (a type of cancer affecting the lymph nodes) received half-body radiotherapy, where radiation was delivered to one side of their body at a time. After treatment, 11 of the dogs showed a noticeable decrease in tumor size, and five dogs achieved either complete or partial remission, lasting an average of about 102 days and 54 days, respectively. The study found that dogs with larger tumors or those that were resistant to chemotherapy had a poorer response to this treatment.

People also search for: dog lymphoma treatment · half-body radiotherapy for dogs · canine cancer remission · lymphoma symptoms in dogs · dog cancer treatment options

Abstract

Abstarct In a Phase I–II study, half-body radiotherapy was used to treat 14 dogs with multicentric lymphoma. Using this technique, a radiation dose of 7 Gray (Gy) was delivered to one half of the body in a single exposure. The other half of the body was treated approximately 28 days later. Of 14 treated dogs, 11 (79%) had a measurable decrease in tumor size. Five dogs achieved a complete or partial remission with a mean duration of 102 and 54 days, respectively. In predicting response to therapy, poor prognostic factors included large tumor burdens, advanced disease stage, and chemotherapy-resistant tumors.

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Original publication on Crossref: https://doi.org/10.1111/j.1939-1676.1989.tb03087.x