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Peer-reviewed veterinary case report

Half-Body Radiotherapy in the Treatment of Canine Lymphoma

Journal:
Journal of Veterinary Internal Medicine
Year:
1989
Authors:
Laing, Elizabeth J. et al.
Affiliation:
Departments of Clinical Studies and Pathology Ontario Veterinary College , Guelph, Ontario · Canada
Species:
dog

Abstract

Abstarct In a Phase I–II study, half-body radiotherapy was used to treat 14 dogs with multicentric lymphoma. Using this technique, a radiation dose of 7 Gray (Gy) was delivered to one half of the body in a single exposure. The other half of the body was treated approximately 28 days later. Of 14 treated dogs, 11 (79%) had a measurable decrease in tumor size. Five dogs achieved a complete or partial remission with a mean duration of 102 and 54 days, respectively. In predicting response to therapy, poor prognostic factors included large tumor burdens, advanced disease stage, and chemotherapy-resistant tumors.

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Original publication: https://doi.org/10.1111/j.1939-1676.1989.tb03087.x