Peer-reviewed veterinary case report
Mineral deposits in brain medulla hamartoma in a dog
By Ide, Tetsuya et al.·Published in The Journal of veterinary medical science·2009·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: Hamartoma in the medulla oblongata with marked mineral deposits in a dog.
- Species:
- dog
Plain-English summary
A 9-year-old female Golden Retriever was diagnosed with a mass in her brainstem, specifically in the medulla oblongata. The mass was about 1 to 2 cm in size and contained unusual mineral deposits, but it was not cancerous. The growth showed very little activity, indicating it was a hamartoma, which is a type of benign growth made up of normal tissue. Since the mass was not aggressive, the dog may not have required immediate treatment, but further monitoring would be essential.
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Abstract
A mass lesion in the medulla oblongata in a 9-year-old female Golden Retriever was examined pathologically. The medullary mass was 1 to 2 cm in diameter and poorly demarcated. The cut surface was discolored with numerous sand-like materials. Histologically, the mass lesion consisted of complex proliferation of irregularly arranged vessels as well as astrocytes with numerous mineral deposits. The astrocytic components exhibited no apparent anaplastic morphology. The proliferating vessels were either veins with muscle layer and capillaries. A few axons and myelinated fibers were also found in the lesion. The number of ki-67-positive cell nuclei was extremely small, suggesting the poor growth activity of these cells. Based on the findings, the lesion was considered to be a non-neoplastic, hamartomatous change.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19721366/