Peer-reviewed veterinary case report
Blood test differences in dogs with large B-cell lymphoma
By Gavazza, Alessandra et al.·Published in Open Veterinary Journal·2024·View original on Crossref →
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Original publication title: Hematological ratios and indices in canine large B-cell lymphoma
- Species:
- dog
Plain-English summary
A group of dogs diagnosed with large B-cell lymphoma, a common type of cancer, had their blood tested to look for signs that could help predict how well they might respond to treatment. The study compared their blood results with those of healthy dogs and found some differences, like anemia (low red blood cells) and high white blood cell counts. However, these blood changes did not seem to affect how long the dogs lived after receiving chemotherapy. While some blood ratios might help in understanding the disease better, more research is needed to determine their true value in predicting outcomes for dogs with lymphoma.
People also search for: dog lymphoma symptoms · canine cancer blood test results · chemotherapy for dog lymphoma
Abstract
Background: Canine lymphoma is the most common hematopoietic cancer in dogs. Numerous studies have evaluated the prognostic value of hematological abnormalities and ratios in both humans and dogs with lymphoma. Aim: To compare hematological parameters and complete blood count ratios between a population of dogs affected by lymphoma and healthy dogs to identify potential prognostic markers for lymphoma. Methods: This retrospective case-control study compares hematological parameters and complete blood count ratios between a population of 114 dogs affected by Multicentric Large B-Cell Lymphoma (LBCL) and 60 healthy dogs. Results: The study found several statistically significant differences between the hematological indices of LBCL dogs and healthy dogs, but no correlation between these parameters and the survival times of 78 dogs treated with chemotherapy Madison Wisconsin Protocol. Additionally, hematological alterations were evaluated such as anemia, leukocytosis, and thrombocytopenia. Conclusion: Hematological ratios have been suggested as potential prognostic markers for canine LBCL but their real prognostic value remains controversial and requires future investigation.
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Search related cases →Original publication on Crossref: https://doi.org/10.5455/ovj.2024.v14.i4.5