Peer-reviewed veterinary case report
Blood test changes in dogs with large B-cell lymphoma
By A. Gavazza et al.·Published in Open Veterinary Journal·2024·View original on Semantic Scholar →
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Original publication title: Hematological ratios and indices in canine large B-cell lymphoma
- Species:
- dog
Plain-English summary
A group of 114 dogs with multicentric large B-cell lymphoma (a type of cancer) was compared to 60 healthy dogs to see if blood tests could help predict how well the dogs would do with treatment. The study found differences in blood counts between the sick and healthy dogs, such as anemia (low red blood cells), but these changes did not help predict how long the dogs would survive after receiving chemotherapy. While some blood ratios might be useful for understanding lymphoma in dogs, more research is needed to confirm their value.
People also search for: dog lymphoma treatment · canine cancer blood test results · dog anemia symptoms
Abstract
Background: Canine lymphoma is the most common hematopoietic cancer in dogs. Numerous studies have evaluated the prognostic value of hematological abnormalities and ratios in both humans and dogs with lymphoma. Aim: To compare hematological parameters and complete blood count ratios between a population of dogs affected by lymphoma and healthy dogs to identify potential prognostic markers for lymphoma. Methods: This retrospective case-control study compares hematological parameters and complete blood count ratios between a population of 114 dogs affected by multicentric large B-cell lymphoma (LBCL) and 60 healthy dogs. Results: The study found several statistically significant differences between the hematological indices of LBCL dogs and healthy dogs, but no correlation between these parameters and the survival times of 78 dogs treated with chemotherapy Madison Wisconsin protocol. In addition, hematological alterations were evaluated such as anemia, leukocytosis, and thrombocytopenia. Conclusion: Hematological ratios have been suggested as potential prognostic markers for canine LBCL but their real prognostic value remains controversial and requires future investigation.
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Search related cases →Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/38808287